Hydrazinecarboxylic acid, 2-[(3-hydroxyphenyl)methylene]-, 1,1-dimethylethyl ester
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester
CAS: 162739-81-3
Molecular Formula: C12H16N2O3
Hydrazinecarboxylic acid, 2-[(3-hydroxyphenyl)methylene]-, 1,1-dimethylethyl ester - Names and Identifiers
| Name | N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester |
| Synonyms | 3-N-BOC-HYDRAZONMETHYLPHENOL tert-Butyl 2-(3-hydroxybenzylidene)hydrazinecarboxylate N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester Hydrazinecarboxylic acid, 2-[(3-hydroxyphenyl)methylene]-, 1,1-dimethylethyl ester |
| CAS | 162739-81-3 |
Hydrazinecarboxylic acid, 2-[(3-hydroxyphenyl)methylene]-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C12H16N2O3 |
| Molar Mass | 236.27 |
Hydrazinecarboxylic acid, 2-[(3-hydroxyphenyl)methylene]-, 1,1-dimethylethyl ester - Introduction
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester is an organic compound whose structural formula is C10H15NO3.
Nature:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester is a white or off-white crystalline solid with low solubility. It is stable at room temperature, but may decompose at high temperatures. It is stable under acidic conditions and may react under basic conditions.
Use:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester is an important intermediate for the synthesis of organic compounds. It can be used as a protecting group in drug synthesis and can be removed by deprotecting group reaction. In addition, it can also be used in organic catalytic reactions and palladium catalytic reactions for the construction of chemical bonds.
Method:
A commonly used preparation method is to obtain N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester by protecting group reaction of phenol. The specific step is to react phenol with N-tert-butoxycarbonylhydrazide, to carry out the reaction under alkaline conditions, and to obtain the target product.
Safety Information:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester has low toxicity under normal operating conditions. However, as an organic compound, it is still necessary to pay attention to protective measures when using or handling. Contact with skin and eyes should be avoided and it should be ensured that the operation is carried out in a well-ventilated place. When handling the compound, wear appropriate protective gloves and glasses, and take proper waste disposal measures.
Nature:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester is a white or off-white crystalline solid with low solubility. It is stable at room temperature, but may decompose at high temperatures. It is stable under acidic conditions and may react under basic conditions.
Use:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester is an important intermediate for the synthesis of organic compounds. It can be used as a protecting group in drug synthesis and can be removed by deprotecting group reaction. In addition, it can also be used in organic catalytic reactions and palladium catalytic reactions for the construction of chemical bonds.
Method:
A commonly used preparation method is to obtain N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester by protecting group reaction of phenol. The specific step is to react phenol with N-tert-butoxycarbonylhydrazide, to carry out the reaction under alkaline conditions, and to obtain the target product.
Safety Information:
N'-(3-Hydroxy-benzylidene)-hydrazinecarboxylic acid tert-butyl ester has low toxicity under normal operating conditions. However, as an organic compound, it is still necessary to pay attention to protective measures when using or handling. Contact with skin and eyes should be avoided and it should be ensured that the operation is carried out in a well-ventilated place. When handling the compound, wear appropriate protective gloves and glasses, and take proper waste disposal measures.
Last Update：2024-04-09 20:52:54
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